Amplimune 5mL (5 Doses)

Amplimune is a one-time immunotherapeutic treatment for calves 1 to 5 days old. Amplimune is used to reduce mortality and clinical signs associated with calf scours caused by E. coli K99. Administer 1 ml intravenously. Amplimune, mycobacterium cell wall fraction (MCWF) immunostimulant, is approved by the USDA for the treatment of bovine infectious disease. Amplimune is recommended as a one-time immunotherapeutic treatment for the reduction of clinical signs and mortality associated with enterotoxigenic Escherichia coli (ETEC) K99 diarrhea in neonatal calves. Colibacillosis caused by ETEC K99 is one of the principal causes of neonatal calf diarrhea. ETEC infection occurs most frequently in the first week of life, before the calf can become resistant to the disease.

Early treatment of colibacillosis must be directed toward the control of the bacteria in the intestinal tract. Studies indicate that the optimum times at which to administer Amplimune are:

1. Early in the disease process, and
2. On farms with persistent E. coli scours, treating all calves immediately, one day after birth.

Studies have shown that a single, 1 mL dose of Amplimune can induce an immediate innate immune response in the neonatal calf to minimize and control the damage caused by pathogenic E. coli. Therefore, the calf's ability to overcome the disease challenge is greatly enhanced. As an alternative to antibiotics, Amplimune, with or without fluid therapy, is effective against colibacillosis. Amplimune is a low volume, single-dose intravenous (IV) therapy. It is OMRI Listed for use in organic cattle production.

PRECAUTION
Store at 2°C-7°C (35°F-45°F). Do not freeze. Use entire contents when first opened. Contains gentamicin as a preservative. Do not administer within 21 days of slaughter. In case of anaphylaxis, administer epinephrine.

Dosage
Aseptically administer 1 ml intravenously. 21 day slaughter withdrawal.

Amplimune 5mL (5 Doses) Highlights:

• SKU: 12706
• Manufacturer: Novavive USA
• Store at 2°C-7°C (35°F-45°F). Do not freeze
• Use entire contents when first opened
• Contains gentamicin as a preservative
• Do not administer within 21 days of slaughter
• In case of anaphylaxis, administer epinephrine
• One time, low volume injection is economical and labor saving
• Stimulates calf’s own natural immune system
• 90% survival rate in a K99 E. coli disease study challenge