Amplimune 20 mL (20 Doses)

Amplimune, mycobacterium cell wall fraction (MCWF) immunostimulant, is approved by the USDA for the treatment of bovine infectious disease. Amplimune is recommended as a one-time immunotherapeutic treatment for the reduction of clinical signs and mortality associated with enterotoxigenic Escherichia coli (ETEC) K99 diarrhea in neonatal calves.

Colibacillosis caused by ETEC K99 is one of the principal causes of neonatal calf diarrhea. ETEC infection occurs most frequently in the first week of life, before the calf can become resistant to the disease. Early treatment of colibacillosis must be directed toward the control of the bacteria in the intestinal tract. Studies indicate that the optimum times at which to administer Amplimune are:

1. Early in the disease process

2. On farms with persistent E. coli scours, treating all calves immediately, one day after birth.

Studies have shown that a single, 1 mL dose of Amplimune can induce an immediate innate immune response in the neonatal calf to minimize and control the damage caused by pathogenic E. coli. Therefore, the calf's ability to overcome the disease challenge is greatly enhanced. As an alternative to antibiotics, Amplimune, with or without fluid therapy, is effective against colibacillosis. Amplimune is a low volume, single-dose intravenous (IV) therapy. It is OMRI Listed for use in organic cattle production.

For use in calves 1-5 days of age, as a one-time immunotherapeutic treatment for reduction of mortality and clinical signs associated with calf scours caused by E. coli K99 diarrhea in neonatal calves.

Dosage: Aseptically administer 1 ml intravenously. 21 day slaughter withdrawal.

Early administration in the disease process stimulates non-antigen related defense mechanisms and enhances calf's innate immune defense system to minimize and control damage caused by pathogenic E. coli.

Amplimune 20 mL (20 Doses) Highlights:

• SKU: 12707
• Manufacturer: Novavive USA
• Early in the disease process
• It is OMRI Listed for use in organic cattle production.
• Amplimune is a low volume, single-dose intravenous (IV) therapy.
• Colibacillosis caused by ETEC K99 is one of the principal causes of neonatal calf diarrhea.
• On farms with persistent E. coli scours, treating all calves immediately, one day after birth.