Amoxi-Mast Rx [12ct]

The amoxicillin in Amoxi-Mast is bactericidal, working against many susceptible bacteria and organisms. This comprehensive antibiotic works to treat many common pathogens that cause infectious mastitis, including penicillin-susceptible Staphylococcus aureus and Streptococcus agalactiae. Amoxi-Mast is a stable, nonirritating suspension of amoxicillin trihydrate containing the equivalent of 62.5 mg of amoxicillin per disposable syringe. Amoxi-Mast is manufactured by a non-sterilizing process. Amoxicillin trihydrate is a semisynthetic penicillin derived from the penicillin nucleus, 6-amino-penicillanic acid. Chemically, it is D (-)-α-amino-p-hydroxybenzyl penicillin trihydrate.

Milk out completely. Wash udder and teat thoroughly with warm water containing a suitable dairy antiseptic. Dry thoroughly. Clean and disinfect the teat with alcohol swabs provided in the carton. Remove the syringe tip cover and insert the tip of the syringe into the teat orifice. Express the suspension into the quarter with gentle and continuous pressure. Withdraw the syringe and grasp the end of the teat firmly. Massage the medication up into the milk cistern. For optimum response, the drug should be administered by intramammary infusion in each infected quarter as described above. Treatment should be repeated at 12-hour intervals for a total of 3 doses. At the next routine milking after the last dose, the treated quarter should be milked out and the milk discarded.

Action: Amoxicillin is bactericidal in action against susceptible organisms. It is a broad-spectrum antibiotic which is effective against common infectious mastitis pathogens, namely Streptococcus agalactiae and penicillin-sensitive Staphylococcus aureus. In vitro studies have demonstrated the susceptibility of the following strains of bacteria: α- and β-hemolytic streptococci, non-penicillinase-producing staphylococci, and Escherichia coli. Susceptibility has not been demonstrated against penicillinase-producing bacteria, particularly resistant staphylococci. Most strains of Pseudomonas, Klebsiella, and Enterobacter is resistant. The clinical or subclinical significance of these in vitro studies is not known.

Indications: Amoxi-Mast is indicated in the treatment of subclinical infectious bovine mastitis in lactating cows due to Streptococcus agalactiae and penicillin-sensitive Staphylococcus aureus. Early detection and treatment of mastitis is advised.

Warnings: Milk taken from animals during treatment and for 60 hours (5 milkings) after the last treatment must not be used for food. Treated animals must not be slaughtered for food purposes within 12 days after the last treatment.

Precaution: Because it is a derivative of 6-amino-penicillanic acid, Amoxi-Mast has the potential for producing allergic reactions. Such reactions are rare; however, should they occur, the subject should be treated with the usual agents (antihistamines, pressor amines).  Administration of this product in any manner other than described under Dosage and Administration may result in drug residues.

Dosage/Administration: Milk out completely. Wash udder and teat thoroughly with warm water containing a suitable dairy antiseptic. Dry thoroughly. Clean and disinfect the teat with alcohol swabs provided in the carton. Remove the syringe tip cover and insert the tip of the syringe into the teat orifice. Express the suspension into the quarter with gentle and continuous pressure. Withdraw the syringe and grasp the end of the teat firmly. Massage the medication up into the milk cistern. For optimum response, the drug should be administered by intramammary infusion in each infected quarter as described above. Treatment should be repeated at 12-hour intervals for a total of 3 doses. At the next routine milking after the last dose, the treated quarter should be milked out and the milk discarded. Each carton contains 12 alcohol swabs to facilitate proper cleaning and disinfecting of the teat orifice.

How Supplied: Amoxi-Mast is supplied in cartons of 12 single-dose syringes with 12 alcohol swabs. Each 10-mL disposable syringe contains amoxicillin trihydrate equivalent to 62.5 mg of amoxicillin activity.

Amoxi-Mast - RX

• SKU: 17128
• Manufacturer: Merck Animal Health
• Available in short tip tubes
• Do not store above 24 degrees C (75 degrees F)
• Demonstrated 86% cure rate for Streptococcus agalactiae, the target of lactating cow Therapy in the U.S
• Broad-spectrum therapy against the major mastitis-causing agents Strep. agalactiae and penicillin-sensitive Staphylococcus aureus
• Consistently associated with increased cure rates for subclinical mastitis
• Economical 60-hour milk withhold
• Useful in treating lactating cattle for subclinical infectious bovine mastitis
• Bactericidal against Streptococcus agalactiae and Staphylococcus aureus susceptible to penicillin
• A stable and non-irritating suspension